You are using an outdated browser. Please upgrade your browser to improve your experience and security.
Median effective dose

Median effective dose

Alternative Titles: 50-percent-effective dose, ED50, ED50

Learn about this topic in these articles:

drug action

  • Prozac
    In drug: Dose-response relationship

    A useful measure is the median effective dose, ED50, which is defined as the dose producing a response that is 50 percent of the maximum obtainable. ED50 values provide a useful way of comparing the potencies of drugs that produce physiologically similar effects at different concentrations. Sometimes the response is…

    Read More

host resistance

  • Haiti earthquake of 2010: cholera
    In disease: Host resistance

    This dose is called the median effective dose, or ED50. It is related in inverse fashion to virulence and in a direct way to resistance. In other words, in a given host, the higher the ED50, the less virulent the infective organism; or, with a microorganism of known virulence, the…

    Read More
Your preference has been recorded
Check out Britannica's new site for parents!
Subscribe Today!